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Glicosilação de exossomas de células de carcinoma do ovário

O cancro de ovário é a causa principal de morte por cancros ginecológicos em muitos países ocidentais. Uma característica do fenótipo da célula tumoral consiste em alterações na glicosilação de glicoproteínas de superfície celular. Exossomas são vesículas secretadas por células humanas, incluindo células tumorais, e também são glicosilados, sendo detectados em fluidos biológicos o que lhes confere relevância em diagnóstico. Os exossomas têm composições proteica e lipídica características, no entanto, os resultados relativos a composição em glicoproteínas e glicosilação são escassos.

Comparative analysis of familial vs sporadic papillary thyroid carcinoma shows a similar clinical/prognostic behaviour

The aim of this study was to compare the potential biological and clinical aggressiveness of familial vs sporadic papillary thyroid carcinoma (PTC), by assessing clinicopathological characteristics, survival parameters and DNA ploidy in two series of 107 patients, matched by age, gender, disease extension and follow-up duration. The results showed higher presence of tumour multifocality in familial PTC (index cases) and a trend to higher occurrence of extrathyroidal extension in the familial PTC subgroup with three or more affected elements.

A análise comparativa do carcinoma papilar da tiroide familiar vs esporádico revela um comportamento clínico/prognóstico semelhante

O objectivo deste trabalho foi comparar a potencial agressividade biológica e clínica do carcinoma papilar da tiróide (CPT) familiar vs esporádico, determinando características clinico-patológicas, parâmetros de sobrevivência e a ploidia do ADN em duas séries de 107 doentes, pareados por idade, género, extensão da doença e tempo de seguimento. Os resultados mostraram maior presença de multifocalidade tumoral no CPT familiar (casos índex) e tendência para maior ocorrência de extensão extratiroideia no subgrupo familiar com três ou mais elementos afectados.

19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine

Metropolitan Hotel, Athens, Greece

 

9 - 11 October 2014

 

See more informations here: http://www.spandidos-publications.com/pages/conference

19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine

Metropolitan Hotel, Athens, Greece

 

9 - 11 October 2014

 

See more informations here: http://www.spandidos-publications.com/pages/conference

Targeting VEGF-mediated Tumor Angiogenesis in Cancer Therapy

The New York Academy of Sciences, 7 World Trade Center, New York, United States


19 - 20 June 2014

 

See more informations here: http://www.nyas.org/Events/Detail.aspx?cid=ae4093af-7d17-4eb4-ac29-93118c62cb52

Targeting VEGF-mediated Tumor Angiogenesis in Cancer Therapy

The New York Academy of Sciences, 7 World Trade Center, New York, United States


19 - 20 June 2014

 

See more informations here: http://www.nyas.org/Events/Detail.aspx?cid=ae4093af-7d17-4eb4-ac29-93118c62cb52

2nd Anticancer Agents Congress:Targeting Cancer Stem Cells

Kervansaray Bodrum Resort Hotel, Bodrum, Turkey

 

23 – 27 April, 2014 

 

See more informations here: http://www.cancerresearch2014.org/

2nd Anticancer Agents Congress:Targeting Cancer Stem Cells

Kervansaray Bodrum Resort Hotel, Bodrum, Turkey

 

23 – 27 April, 2014 

 

See more informations here: http://www.cancerresearch2014.org/

Apply for an EACR Travel Fellowship in 2014

Eligible EACR members can now apply for an EACR Travel Fellowship at any time and hear the result within 10 working days. 
 

EACR's Travel Fellowships scheme, co-sponsored by the Association for International Cancer Research (AICR), offers researchers with less than four years postdoctoral experience (including PhD students) the opportunity to advance their research by visiting a centre of excellence in another country.