Tumor Microenvironment

The therapeutic landscape in breast cancer has benefited from the development of variate antibody-based therapies. Yet, pre-clinical models capable of recapitulating the complex crosstalk within the tumor microenvironment (TME) are needed to properly address the effect of such therapies. In this work, we devised cell models able to accommodate different cell populations (3D-3), by adding stromal and immune components to multicellular tumor spheroids. The models were microencapsulated in alginate and kept under stirred conditions, to recreate critical hallmarks of the TME.

i3S, Porto, Portugal

26 -27 October, 2023

See more informations here: https://aspicaseicameeting.aspic.pt/

i3S, Porto, Portugal

26 -27 October, 2023

See more informations here: https://aspicaseicameeting.aspic.pt/

Authors and Affiliations:

Flávia Pereira ^1,2,3,4, Anabela Ferreira ^1,2, Celso Albuquerque Reis ^3,5,6, Maria João Sousa ^1,2, Maria José Oliveira ^3,4,5 and Ana Preto ^1,2

¹ Centre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal

Virtual Event, Worldwide

14 - 16 February 2022

See more informations here: https://iecc2022.sciforum.net/

Virtual Event, Worldwide

14 - 16 February 2022

See more informations here: https://iecc2022.sciforum.net/

Authors and affiliations:
Joana Maia^1,2, Andreia Hanada Otake^1,3, Juliana Poças^4,5,6, Ana Sofia Carvalho⁷, Hans Christian Beck⁸, Ana Magalhães^4,5, Rune Matthiesen⁷, Maria Carolina Strano Moraes¹ and Bruno Costa-Silva¹

1-Champalimaud Centre for the Unknown, Champalimaud Foundation, Lisbon, Portugal

2-Graduate Program in Areas of Basic and Applied Biology, University of Porto, Porto, Portugal