HMGA1

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A new study reveals that HMGA1 promotes cancer stem-like traits and increases sensitivity to monensin in gastric cancer cells

Researchers from the "Differentiation and Cancer" group at i3S, in collaboration with António Pombinho, from the "BioSciences Screening" platform, and Filipe Pereira, from Lund University, elucidated the role of the transcription factor HMGA1 in gastric cancer stem cells. The study, entitled "HMGA1 stimulates cancer stem-like features and sensitivity to monensin in gastric cancer," was recently published in the journal "Experimental Cell Research."

Um novo estudo revela que o HMGA1 estimula as características estaminais e aumenta a sensibilidade à monensina em células de cancro gástrico

Investigadores do grupo “Diferenciação e Cancro” do i3S, em colaboração com António Pombinho, da plataforma “BioSciences Screening”, e Filipe Pereira, da Universidade de Lund, elucidaram o papel do fator de transcrição HMGA1 nas células estaminais de cancro gástrico. O estudo, intitulado “HMGA1 stimulates cancer stem-like features and sensitivity to monensin in gastric cancer”, foi recentemente publicado na revista “Experimental Cell Research”.