breast cancer

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Aneuploidy identifies subsets of patients with poor clinical outcome in grade 1 and grade 2 breast cancer

In this study, which included 684 patients with invasive breast carcinoma and long-term follow-up, we observed that those who presented grade 1 and grade 2 aneuploid tumours, as compared with diploid ones, had worse prognosis, either in the whole series or in early breast cancer (stages I/IIA of disease). The finding has therapeutic implications, as these patients are potential candidates to risk-adapted adjuvant therapy.

 

Authors and Affiliations:

Anti-influenza inhibitor favours tumour aggressiveness in a canine model of breast cancer

Authors and Affiliations:

Joana T. de Oliveira1,2,3,4, Ana L. Santos1,2, Catarina Gomes1,2, Rita Barros1,2, Cláudia Ribeiro1,2, Nuno Mendes1,2, Augusto J. de Matos3,5, M. Helena Vasconcelos1,2,6, Maria José Oliveira1,7,8, Celso A. Reis1,2,3,8, Fátima Gärtner1,2,3

A meta-analysis to evaluate the cellular processes regulated by the interactome


Joana Simões1, Francisco M. Amado1,2, Rui Vitorino1,3,* and Luisa A. Helguero1,3,*

1 Mass Spectrometry Centre, QOPNA Research Unit, Department of Chemistry, Universidade de Aveiro, Campus Universitário de Santiago, Aveiro, Portugal

2 School of Healh Sciences, Universidade de Aveiro, Portugal

Management of locally advanced breast cancer - perspectives and future directions

Authors and Affiliations:

Tryfonidis K1, Senkus E2, Cardoso MJ3, Cardoso F3.

1European Organisation for Research and Treatment of Cancer (EORTC) Headquarters &Breast Cancer Group, Avenue Mounier 83/11, 1200 Brussels, Belgium.

2Department of Oncology and Radiotherapy, Medical University of Gdansk, Ul Debinki 7, 80211 Gdansk, Poland.

3Breast Unit, Champalimaud Clinical Centre, Avenida De Brasília s/n, 1400-038 Lisbon, Portugal

Management of locally advanced breast cancer - perspectives and future directions

Autores e Afiliações:

Tryfonidis K1, Senkus E2, Cardoso MJ3, Cardoso F3.

1European Organisation for Research and Treatment of Cancer (EORTC) Headquarters &Breast Cancer Group, Avenue Mounier 83/11, 1200 Brussels, Belgium.

2Department of Oncology and Radiotherapy, Medical University of Gdansk, Ul Debinki 7, 80211 Gdansk, Poland.

3Breast Unit, Champalimaud Clinical Centre, Avenida De Brasília s/n, 1400-038 Lisbon, Portugal

 

The P-cadherin expression is associated with breast cancer cells with glycolytic phenotype

Bárbara Sousa 1,2, Ana Sofia Ribeiro 1, Ana Rita Nobre 1, Nair Lopes 1, Diana Martins 1, Céline Pinheiro 3,4, André Filipe Vieira 1, André Albergaria 1,5, René Gerhard 1, Fernando Schmitt 1,5, Fátima Baltazar 3,4
 and Joana Paredes 1,5

1 Iptimup- Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal;

Evaluation of axillary dose coverage following whole breast radiotherapy: Variation with the breast volume and shape

Even though this is not the first investigation addressing axillary dose coverage in patients submitted to tridimensional whole breast radiotherapy, this particular study aimed at evaluating the impact of the breast volume and shape in the dose reaching all three axillary levels, in early stage breast cancer patients.

IMPAKT 2015 Breast Cancer Conference

SQUARE Brussels Meeting Centre, Brussels, Belgium

 

07 - 09 May, 2015

 

See more informations here: http://www.esmo.org/Conferences/IMPAKT-2015-Breast-Cancer

IMPAKT 2015 Breast Cancer Conference

SQUARE Brussels Meeting Centre, Brussels, Belgium

 

07 - 09 May, 2015

 

See more informations here: http://www.esmo.org/Conferences/IMPAKT-2015-Breast-Cancer

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

Authors and Affiliations:

Sonia A. Melo1, 2, Hikaru Sugimoto1, 2, Joyce T. O’Connell2, Noritoshi Kato2, Alberto Villanueva3, August Vidal4, Le Qiu5, Edward Vitkin5, Lev T. Perelman5, Carlos A. Melo6, 7, Anthony Lucci8, Cristina Ivan9, George A. Calin10, Raghu Kalluri1, 2,