therapeutic targets

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Extracellular vesicles in tumor-adipose tissue crosstalk: key drivers and therapeutic targets in cancer cachexia

More than half of all advanced cancer patients will experience cachexia at any point in their disease. Patients with cancer cachexia often experience unintentional weight loss mainly due to the progressive loss of body fat and skeletal muscle. This metabolic disorder severely impacts patients’ quality of life, treatments, and survival. Although nutritional supplementation is recommended in cancer cachexia patients, this solution is not capable of reversing cachexia symptoms.