The study "Combination of gold nanoparticles with near-infrared light as an alternative approach for melanoma management" investigated the combination of gold nanoparticles with near-infrared laser irradiation as a promising therapeutic strategy for melanoma treatment. The different assays conducted demonstrated nanoparticles or the laser alone did not cause significant cytotoxic effects. In contrast, the combined therapy substantially reduced cell viability and induced cell death through an apoptotic mechanism.