Tânia Santos de Almeida

Rutin is a bioflavonoid widely found in nature that has shown several promising pharmacological properties, including antitumor activity. However, the low solubility of this compound remains one of the limiting factors of its applicability. In the published article “Anticancer Activity of Rutin and Its Combination with Ionic Liquids on Renal Cells”, the antitumor activity of rutin was demonstrated in 786-O cells, an in vitro model of human renal carcinoma, in which this activity had not yet been studied.

A rutina é um bioflavonoide amplamente encontrado na natureza que tem vindo a demonstrar diversas propriedades farmacológicas promissoras, incluindo a atividade antitumoral. No entanto, a baixa solubilidade deste composto continua a ser um dos fatores limitantes da sua aplicabilidade. No artigo publicado “Anticancer Activity of Rutin and Its Combination with Ionic Liquids on Renal Cells” demonstrou-se a atividade antitumoral da rutina em células 786-O, um modelo in vitro de carcinoma renal humano, no qual ainda não havia sido estudada esta atividade.