antitumor activity

Rutin is a bioflavonoid widely found in nature that has shown several promising pharmacological properties, including antitumor activity. However, the low solubility of this compound remains one of the limiting factors of its applicability. In the published article “Anticancer Activity of Rutin and Its Combination with Ionic Liquids on Renal Cells”, the antitumor activity of rutin was demonstrated in 786-O cells, an in vitro model of human renal carcinoma, in which this activity had not yet been studied.

Authors and Affiliations:

Sandra A.C. Figueiredo ^{a, b}, Jorge A.R. Salvador ^{a, b}, Roldán Cortés ^c, Marta Cascante ^c

^a Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, 3000-548, Coimbra, Portugal

^b Centre for Neuroscience and Cell Biology, Coimbra, Portugal

^c Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Institute of Biomedicine, University of Barcelona, Diagonal 643, 08028 Barcelona, Spain.