Society for Immunotherapy of Cancer

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4th Immunotherapy of Cancer Conference

Prague Congress Centre, Prague, Czech Republic

 

20 - 22 March, 2017

 

See more informations here: http://itoc-conference.eu/itoc4

4th Immunotherapy of Cancer Conference

Prague Congress Centre, Prague, Czech Republic

 

20 - 22 March, 2017

 

See more informations here: http://itoc-conference.eu/itoc4

Improved tumor cell models are paramount to overcome current shortcomings of pre-clinical research and drug discovery

The team from the Advanced Cell Models Laboratory in the Animal Cell Technology Unit, based at Instituto de Biologia Experimental e Tecnológica (IBET) and Instituto de Tecnologia Química e Biológica António Xavier (ITQB) has been invested on the development of novel advanced tumor cell models with the ability to recapitulate certain features of tumor microenvironment, namely their heterogeneity and complex cellular composition. It has been demonstrated by several authors that tumor microenvironment plays a major role on tumor progression and drug response.

Modelos celulares tumorais com maior relevância fisiológica são determinantes para ultrapassar actuais limitações na descoberta de novos fármacos

A equipa de investigação do laboratório de Modelos Celulares Avançados na Unidade de Tecnologia de Células Animais, baseada no Instituto de Biologia Experimental e Tecnológica (IBET) e Instituto de Tecnologia Química e Biológica António Xavier (ITQB), tem vindo a investir no desenvolvimento de modelos celulares tumorais que mimetizam características inerentes do microambiente tumoral, nomeadamente o seu elevado nível de heterogeneidade e complexa composição celular.