Low-molecular weight protein tyrosine phosphatase (LMW-PTP) has been associated with tumorigenesis and tumor progression. However, its role remains controversial. In this study we demonstrate that the controversial role of this protein can be due to the paucity of studies focused on its two main isoforms, fast and slow. The differential expression of these isoforms should be taken into account when studying this protein in the context of tumor, namely breast cancer. Our results highlight the role of these isoforms in breast cancer.
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