new therapeutic target

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GPER as a new therapeutic target in melanoma

In this work, the expression of the G-protein coupled receptor (GPER) is reported for the first time in a melanoma cell line, and that its activation by the agonist G-1 decreases cell proliferation, suggesting that the GPER may represent a new therapeutic target in this disease. 

 

Authors and Affiliations:

Mariana P.C. Ribeiro, Armanda E. Santos and José B.A. Custódio