mutant p53

Skin cancer (SC) is one of the most common types of cancer in the world population, with an increasing annual incidence rate. The p53 protein plays a crucial role in skin tumorigenesis, and its function is often compromised due to mutations induced by ultraviolet radiation (UVB). Currently, sunscreen is the most recommended agent for the prevention of SC. However, the growing incidence of this type of cancer has stressed the need for effective protective options complementary to sunscreen.

Authors and affiliations:
Marco M Candeias ^1,2,3,6, Masatoshi Hagiwara^2,4 and Michiyuki Matsuda^1,5

¹Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies Kyoto University, Kyoto, Japan

²Department of Anatomy and Developmental Biology, Graduate School of Medicine Kyoto University, Kyoto, Japan

³Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisboa, Portugal