A researcher group of the Unit for Multidisciplinary Research in Biomedicine (UMIB) led by Professor Mariana P. Monteiro developed a research project, co-financed by the Portuguese Society of Endocrinology Diabetes and Metabolism (SPEDM), whose objective was to evaluate the influence of obesity in androgen independent prostate carcinoma progression. For this purpose, in vitro studies were performed in order to evaluate the effect of factors released by adipocytes and preadipocytes in proliferation, migration and invasion of androgen independent prostate carcinoma cells.