cardiotoxicity

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New mechanism behind Doxorubicin cardiotoxicity

A group of researchers from the Center for Neuroscience and Cell Biology (CNC) at the University of Coimbra (UC), uncovered a new mechanism behind the cardiotoxicity of the anticancer drug Doxorubicin (or Adriamycin) that can be explored in the future as a new therapeutic target to counteract the adverse effects of chemotherapy. Although Doxorubicin is a powerful chemotherapeutic agent, it has severe long-term adverse effects that compromise the cardiac function of patients.