Photoimmunoconjugates

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Photoimmunoconjugates: novel synthetic strategies to target and treat cancer by photodynamic therapy

Photodynamic therapy (PDT) has evolved as a therapeutic modality in the treatment of various types of cancer. The destruction of tumor cells is due to the formation of reactive oxygen species resulting from the interaction between the photosensitizer (PS), light, and oxygen. Recently, the combination of the photosensitizer with antibodies, or with antibody fragments, has contributed to improvements in the specificity of this phototherapy, reducing its side effects.