Nanoparticulate vaccine

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Nanoparticulate vaccine inhibits tumor growth via improved T cell recruitment

This collaborative study between labs in Portugal and Israel describes the development of a vaccine based on polymeric nanoparticles and the analysis of its interaction with targeted immune cells. This vaccine was able to extensively enhance the infiltration of T cells into the tumor microenvironment, which dramatically inhibited the disease progression in mouse models of melanoma and mammary carcinoma.