immune cells

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1st EACR meeting on the Structural Microenvironment: Breaking down the walls of cancer

The Achilles heel of pro-tumoral γδ ​T cells

Tumors are infiltrated by many immune cells that influence many aspects of cancer progression and outcome. Among tumor-infiltrating lymphocytes, γδ T cells play dual functions in the tumor milieu; whereas those that produce the antitumor cytokine interferon-γ are protective, their counterparts that make interleukin 17 (IL-17) support tumor growth. Here, the authors found that IL-17+ γδ T cells express very low levels of the antioxidant, glutathione, and are very sensitive to reactive oxygen species (ROS), thus revealing their Achilles' heel.

CRUK Beatson Institute Workshop: Understanding Tumour Immunology

Cancer Research UK Beatson Institute, Glasgow, United Kingdom

 

03 - 04 September, 2017

 

See more informations here: http://www.beatson.gla.ac.uk/Beatson-Workshop/beatson-workshop.html

CRUK Beatson Institute Workshop: Understanding Tumour Immunology

Cancer Research UK Beatson Institute, Glasgow, United Kingdom

 

03 - 04 September, 2017

 

See more informations here: http://www.beatson.gla.ac.uk/Beatson-Workshop/beatson-workshop.html

Genes and Cancer – 32nd Annual meeting

Robinson College at the University of Cambridge, Cambridge, United Kingdom

 

10 - 12 April, 2017

 

See more informations here: http://www.genesandcancer.org.uk/

Genes and Cancer – 32nd Annual meeting

Robinson College at the University of Cambridge, Cambridge, United Kingdom

 

10 - 12 April, 2017

 

See more informations here: http://www.genesandcancer.org.uk/

Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities