B-cell malignancies

envie a um amigo share this

Current challenges and emerging opportunities of CAR-T cell therapies

During the past few years, the establishment of immunotherapy (e.i. stimulation of the immune system to recognize and kill malignant cells) as a reliable therapeutic option to tackle cancer, has shifted the paradigm of cancer treatment. Among the different classes of cancer immunotherapies, including checkpoint inhibitor monoclonal antibodies (2018 Nobel Prize Physiology or Medicine), adoptive T cell therapies (ACTs), harboring CAR-T cells, are emerging as a revolutionary strategy to eliminate tumors.

As células CAR-T no combate ao cancro - desafios atuais e oportunidades futuras

O estabelecimento da imunoterapia - estimulação do sistema imunitário para que este reconheça e destrua as células tumorais - como uma abordagem terapêutica eficaz no combate ao cancro, é, indubitavelmente, um dos maiores marcos no tratamento das doenças oncológicas dos últimos anos.