Skin Cancer

Authors and Affiliations:

Patrícia Correia¹, Paula Araújo¹, Joana Marto², Helena Ribeiro², Nuno Mateus¹, Victor de Freitas¹, Joana Oliveira¹ & Iva Fernandes¹

¹REQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal.

Hofburg Vienna, Austria

31 August - 03 September 2016

See more informations here: http://www.wccs2016.com/

Hofburg Vienna, Austria

31 August - 03 September 2016

See more informations here: http://www.wccs2016.com/

The Department of Radiotherapy of Hospital de Santa Maria has already published in Brachytherapy, the journal of American Society of Brachytherapy, the results of 17 cases of eyelid carcinomas treated with high-dose-rate interstitial brachytherapy. It is the publication with the largest number of basal cell carcinomas undergoing this type of treatment and the second largest in terms of total number of lesions, including basal and squamous cell carcinomas. With a median followup of 40 months, the local control rate was 94.1%, similar to that achieved with other treatments, including surgery.

O Serviço de Radioterapia do Hospital de Santa Maria publicou recentemente, na revista norte-americana Brachytherapy, o resultado de 17 casos de carcinomas da pálpebra tratados com braquiterapia intersticial de alta taxa de dose. Trata-se da publicação com maior número de basaliomas submetidos a este tipo de tratamento e a segunda maior em termos de número total de lesões, incluindo basaliomas e carcinomas pavimento-celulares. Com um followup mediano de 40 meses, a taxa de controlo local foi de 94,1%, semelhante à alcançada com outros tratamentos, incluindo a cirurgia.

A team of IPATIMUP researchers had previously demonstrated that alterations in the telomerase gene are common to different types of cancer, including tumors of the skin, brain, bladder, and thyroid and are associated with increased levels of this enzyme in tumors. The same team now published a study in Journal of Investigative Dermatology, where they analyzed two types of skin cancer, melanoma and basal cell carcinoma, and demonstrates that telomerase gene mutations are associated with sun exposure and are also associated with a poorer prognosis in melanoma.