Researchers from the Epigenetics & Cancer Biology Group at the IPO Porto Research Center, in collaboration with the Pathology and Clinical Pathology Services, have developed an algorithm to improve the screening of women who test positive for HPV infection in the Population Cervical Cancer Screening Program implemented in the Northern region of the country. Based on DNA methylation markers and combined with HPV genotyping information, this algorithm reduces the number of women referred for a Cervical Pathology consultation and possible colposcopy.