Notch signaling pathway

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The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells from different subtypes

Downregulation of DLL1 protein (a ligand of the Notch signaling pathway) decreases the carcinogenic properties of cancer cells from various human breast cancer subtypes in different manners. This study, developed by scientists from iBET, contributes to the knowledge of the mechanisms involved in the pathobiology of breast cancer and to the development of new therapies to target this disease.

 

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