This work recently published in the “International Journal of Cancer" demonstrated the possibility of repurposing pirfenidone (an antifibrotic drug) in combination with vinorelbine or with vinorelbine plus carboplatin for the perioperative treatment of non-small cell lung cancer (NSCLC), with the aim of improving therapeutic efficacy while reducing toxicity. This work resulted from a collaboration between the Cancer Drug Resistance group from i3S and the Experimental Pathology and Therapeutics Group, from IPO Porto.
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