diagnosis

The lack of a sensitive and specific biomarker for early detection of prostate cancer (PCa) is a major obstacle to the effective treatment of these patients. This study aimed to study the volatile urinary metabolic profile of PCa patients (n=58) and control individuals (cancer-free, n=60), to identify a potential panel of biomarkers for non-invasive PCa detection. The results obtained revealed a panel of biomarkers with 6 volatile compounds, which was able to identify this type of cancer with a sensitivity, specificity and accuracy of 89%, 83% and 86%, respectively.

A falta de um biomarcardor sensível e específico para a deteção precoce do cancro da próstata constitui um obstáculo ao tratamento eficaz destes doentes. Este trabalho pretendeu estudar o perfil metabólico volátil de urinas de doentes com cancro da próstata (n=58) e de indivíduos controlo (sem cancro, n=60), com o objetivo de identificar um potencial painel de biomarcadores para a deteção não invasiva do cancro da próstata.

CosmoCaixa Science Museum, Barcelona, Spain

04-06 February, 2018

See more informations here: https://www.eacr.org/conference/trackingcancers2019

CosmoCaixa Science Museum, Barcelona, Spain

04-06 February, 2018

See more informations here: https://www.eacr.org/conference/trackingcancers2019

Authors and Affiliations:

Sílvia Castro Coelho^1, Maria Carmo Pereira^1, Asta Juzeniene^2, Petras Juzenas^2, Manuel Álvaro Coelho¹

 ¹ LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Roberto Frias, PT-4200-465 Porto, Portugal

² Department of Radiation Biology, Institute for Cancer Research, Radiumhospital, Oslo University Hospital, NO-0310 Oslo, Norway

Abstract: