metastasis

Authors and Affiliations:

Tawana Hotel, Conference Centre, Bangkok, Thailand

28 - 30 March, 2019

See more informations here: http://worldacademyofsciences.com/thailand.html

Tawana Hotel, Conference Centre, Bangkok, Thailand

28 - 30 March, 2019

See more informations here: http://worldacademyofsciences.com/thailand.html

Major alterations in cell glycosylation occurring during cancer development and progression represent key features of tumor cell malignant behavior. In this publication, the authors preview and put in context the findings of Agrawal et al. (Cancer Cell, Vol. 31, Issue 6, 2017) that identified and characterized a novel molecular mechanism in which aberrant glycosylation actively tunes the metastatic capacity of melanoma cells by preventing the proteolytic cleavage of the L1CAM adhesion molecule.

Authors and Affiliations:

Major alterations in cell glycosylation occurring during cancer development and progression represent key features of tumor cell malignant behavior. In this publication, the authors preview and put in context the findings of Agrawal et al. (Cancer Cell, Vol. 31, Issue 6, 2017) that identified and characterized a novel molecular mechanism in which aberrant glycosylation actively tunes the metastatic capacity of melanoma cells by preventing the proteolytic cleavage of the L1CAM adhesion molecule.

Autores e Afiliações:

Authors and Affiliations:

Filipe Pinto^1,2 Nathalia C. Campanella³ Lucas F. Abrahão-Machado⁴ Cristovam Scapulatempo-Neto^3,4 Antonio T. de Oliveira^3,5 Maria J. Brito6 Raquel P. Andrade⁷ Denise P. Guimarães^3,8 Rui M. Reis^1,2,3

¹ Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal

² ICVS/3B’s-PT Government Associate Laboratory, Braga, Guimara˜es, Portugal

O factor de transcrição Brachyury foi recentemente descrito como estando sobre-expresso e associado com pior prógnostico em tumores sólidos. No presente estudo avaliamos o potencial valor de prognóstico de Brachyury em tumores do estroma gastrointestinal (GIST).

Authors and affilliations:

Melo SA, Kalluri R.

Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas 

Abstract:

Autores e afiliações:

Melo SA, Kalluri R.

Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas 

Resumo: