canine mammary tumours

Researchers from the Institute of Biomedical Sciences Abel Salazar of the University of Porto, found that VEGFR-2, the major receptor activated by VEGF during angiogenesis, is highly expressed in canine mammary gland carcinosarcomas, a rare tumour type of canine and human breast. This finding reinforces the role of spontaneous canine mammary tumours as a model to study uncommon types of women breast cancer.

Authors and Affiliations:

Santos, A.¹, Lopes, C.², Gärtner, F.^2,3, Matos, A.J.F.^4,5

A group of researchers from IPATIMUP found that the differential expression of galectin-1 and galectin-3 participates in the process of metastasis in a spontaneous canine model of breast cancer.

Authors and Affiliations:

Joana T. de Oliveira^1,2,3, Augusto J. de Matos², Rita Barros¹, Cláudia Ribeiro¹, Asaf Chen¹, Venceslau Hespanhol⁴, Gerard R Rutteman^5,6 and Fátima Gärtner^1,2