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Proteome profiling of urine with mass spectrometry approaches and bioinformatic tools allows an integrative perspective of the biological processes modulated by urothelial carcinoma

Using a well-established animal model of urothelial carcinoma, we performed urine proteome profiling from healthy animals and animals with urothelial carcinoma at two time-points of disease pathogenesis. Data analysis highlighted the biological processes involved in disease pathogenesis such as, for instance, response to selenium and to drugs, neutral lipid metabolism at earlier stages of disease, and inflammation, immune response and wound healing at advanced stages.

 

Authors and Affiliations:

A análise da urina com técnicas de proteómica baseadas em espectrometria de massa e ferramentas bioinformáticas permite obter uma visão integrada dos processos biológicos modulados pelo carcinoma urotelial

A análise de amostras de urina obtidas de um modelo animal de cancro da bexiga em diferentes estadios da doença permitiu identificar os processos biológicos envolvidos na patogênese do carcinoma urotelial, tais como a resposta ao selénio e a drogas e prevalência do metabolismo de lípidos em estadios iniciais e inflamação, resposta imune e fibrose em estadios avançados da doença.

 

Autores e Afiliações:

Rita Ferreira, Rui Vitorino, António Barros, Telma Martins, Sandra Magalhães e Fábio Trindade – Departamento de Química da Universidade de Aveiro

Four researchers in cancer received the Health Marathon Awards

The Health Marathon has announced the winners of the Health Marathon Research Awards, which first edition was dedicated to cancer.

Prémios Maratona da Saúde para quatro investigadores em cancro

A Maratona da Saúde já anunciou os vencedores dos Prémios de Investigação Maratona da Saúde, que nesta primeira edição foram dedicados ao cancro.

ASPIC Conference - Reassembling the cancer clinic: translational research, actionable mutations, and the reframing of cancer clinical trials

Keynote Speaker: Alberto Cambrosio

 

This conference is organized by the Portuguese Association for Cancer Research (ASPIC), the Research Center of IPO-Lisboa Francisco Gentil and Fundação Calouste Gulbenkian.

 

Auditorium IPO-Lisboa Francisco Gentil, 12:00-13:30, May 12, 2015

 

 

Alberto Cambrosio:

McGill University, Canada

 

ASPIC Conference - Reassembling the cancer clinic: translational research, actionable mutations, and the reframing of cancer clinical trials

Keynote Speaker: Alberto Cambrosio

 

This conference is organized by the Portuguese Association for Cancer Research (ASPIC), the Research Center of IPO-Lisboa Francisco Gentil and Fundação Calouste Gulbenkian.

 

Auditorium IPO-Lisboa Francisco Gentil, 12:00-13:30, May 12, 2015

 

 

Alberto Cambrosio:

McGill University, Canada

 

Ana Sofia Ribeiro e Mónica Fernandes premiadas no 1º Congresso da ASPIC

No decorrer do 1º Congresso Internacional da ASPIC, que se realizou a 25 e 26 de Novembro na Fundação Calouste Gulbenkian, em Lisboa, foram premiados os dois melhores posters de um total de 139 posters que estiveram a concurso.

VI InterAmerican Oncology Conference: Current Status and Future of Anti-Cancer Targeted Therapies

Auditorio UCA - Universidad Católica Argentina, Buenos Aires, Argentina

 

8 - 9 October, 2015

 

See more informations here: http://www.oncologyconferences.com.ar/index.html

VI InterAmerican Oncology Conference: Current Status and Future of Anti-Cancer Targeted Therapies

Auditorio UCA - Universidad Católica Argentina, Buenos Aires, Argentina

 

8 - 9 October, 2015

 

See more informations here: http://www.oncologyconferences.com.ar/index.html

2nd ISCaM meeting - Metabolism and Microenvironment in Cancer Plasticy

Venice, Italy

 

16 - 19 September 2015

 

See more informations here: http://www.iscams.org/meetings